The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.a

Pulmonary edema, noncardiogenic (NCPE)

A complication of drug overdose

Publications

Lindeman E, Ålebring J, Johansson A, Ahlner J, Kugelberg FC, Nordmark Grass J

The unknown known: non-cardiogenic pulmonary edema in amlodipine poisoning, a cohort study.

Clinical toxicology (Philadelphia, Pa.) 2020 Mar 02;;1-8 — 2020 Mar 02 — 1-8

Hedaiaty M, Eizadi-Mood N, Sabzghabaee AM

Noncardiogenic Pulmonary Edema after Amlodipine Overdose without Refractory Hypotension and Bradycardia.

Case reports in emergency medicine 2015;2015;546012 — 2015 — 546012

Kute VB, Shah PR, Goplani KR, Gumber MR, Vanikar AV, Trivedi HL

Successful treatment of refractory hypotension, noncardiogenic pulmonary edema and acute kidney injury after an overdose of amlodipine.

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 2011 Jul;15;182-4 — 2011 Jul — 182-4