The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.o

Cardiovascular collapse - Cardiogenic shock - Hypotension

Publications

Ramanathan K, Mohanty B, Tang S, MacLaren G

Extracorporeal therapy for amlodipine poisoning.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2019 Sep 24;; — 2019 Sep 24

Kumar K, Biyyam M, Bajantri B, Nayudu S

Critical Management of Severe Hypotension Caused by Amlodipine Toxicity Managed With Hyperinsulinemia/Euglycemia Therapy Supplemented With Calcium Gluconate, Intravenous Glucagon and Other Vasopressor Support: Review of Literature.

Cardiology research 2018 Feb;9;46-49 — 2018 Feb — 46-49

Kapelios CJ, Karamanakos G, Liatis S, Sarafadi M, Polizois M, Papoutsis I, Kokkinos AD

Recurrent episodes of life-threatening vasodilatory shock following unintentional intoxication with amlodipine.

Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 2017 Sep - Oct;58;369-371 — 2017 Sep - Oct — 369-371

Kute VB, Shah PR, Goplani KR, Gumber MR, Vanikar AV, Trivedi HL

Successful treatment of refractory hypotension, noncardiogenic pulmonary edema and acute kidney injury after an overdose of amlodipine.

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 2011 Jul;15;182-4 — 2011 Jul — 182-4