The Drug-Induced Respiratory Disease Website and App

Angiotensin converting enzyme inhibitors (ACEI)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

V.d

Pleural/pericardial effusion, ANA positive (DI lupus)

Publications

Rosenfeld N, Yeche S, Reynaud D, Abiad L, Dubois A

[Acute disseminated lupus erythematosus. Responsibility of Corenitec: apropos of a case].

Therapie 1999 Jul Aug;54;493-4 — 1999 Jul Aug — 493-4

Pelayo M, Vargas V, Gonzales A, Vallano A, Esteban R, Guardia J

Drug-induced lupus-like reaction and captopril.

The Annals of pharmacotherapy 1993 Dec;27;1541-2 — 1993 Dec — 1541-2

Sieber C, Grimm E, Follath F

Captopril and systemic lupus erythematosus syndrome.

BMJ (Clinical research ed.) 1990 Sep 29;301;669 — 1990 Sep 29 — 669