The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.a

DRES syndrome - DRESS-like reaction

Publications

Nam YH, Park MR, Nam HJ, Lee SK, Kim KH, Roh MS, Um SJ, Son CH

Drug reaction with eosinophilia and systemic symptoms syndrome is not uncommon and shows better clinical outcome than generally recognised.

Allergologia et immunopathologia. 2015;43(1):19-24

Halink DA, Marijnissen RM, Schut AA, Oude Voshaar RC

Drug reaction with eosinophilia and systemic symptoms induced by carbamazepine: DRESSed to kill.

General hospital psychiatry. 2011;33(4):412.e5-8

Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L, Roujeau JC

The DRESS syndrome: a literature review.

The American journal of medicine. 2011;124(7):588-97

Pereira de Silva N, Piquioni P, Kochen S, Saidon P

Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.

European journal of clinical pharmacology. 2011;67(5):463-70

Picard D, Janela B, Descamps V, D'Incan M, Courville P, Jacquot S, Rogez S, Mardivirin L, Moins-Teisserenc H, Toubert A, Benichou J, Joly P, Musette P

Drug reaction with eosinophilia and systemic symptoms (DRESS): a multiorgan antiviral T cell response.

Science translational medicine. 2010;2(46):46ra62

Newell BD, Moinfar M, Mancini AJ, Nopper AJ

Retrospective analysis of 32 pediatric patients with anticonvulsant hypersensitivity syndrome (ACHSS).

Pediatric dermatology. 2009;26(5):536-46

Roujeau JC

Clinical heterogeneity of drug hypersensitivity.

Toxicology. 2005;209(2):123-9

De Vriese AS, Philippe J, Van Renterghem DM, De Cuyper CA, Hindryckx PH, Matthys EG, Louagie A

Carbamazepine hypersensitivity syndrome: report of 4 cases and review of the literature.

Medicine. 1995;74(3):144-51