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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (ILD), acute and/or severe (may produce the ARDS pattern)

Publications

Fu M, Feng CM, Cao LJ, Hu XW, Xu QX, Xia HL, Ji ZM, Hu NN, Xie W, Fang Y, Xia DQ, Zhang JQ

Acute Respiratory Distress Syndrome Caused by Occupational Exposure to Waterproofing Spray: A Case Report and Literature Review.

Frontiers in public health. 2022;10:830429

Futatsuya C, Minato H, Okayama Y, Katayanagi K, Kurumaya H, Yuasa M, Nishi K

An Autopsy Case of Idiopathic Pleuroparenchymal Fibroelastosis with Left Vocal Cord Paralysis and a Rapid Deterioration without an Acute Exacerbation.

Internal medicine (Tokyo, Japan). 2020;59(12):1541-1547

Harada T, Hirabayashi Y, Takayama-Isagawa Y, Sakamoto H, Kawaishi M, Hara H, Aizawa S

Pulmonary Injury from Waterproofing Spray During a Hike.

Wilderness & environmental medicine. 2017;28(4):327-331

Heinzer R, Ribordy V, Kuzoe B, Lazor R, Fitting JW

Recurrence of acute respiratory failure following use of waterproofing sprays.

Thorax. 2004;59(6):541-2

Lazor-Blanchet C, Rusca S, Vernez D, Berry R, Albrecht E, Droz PO, Boillat MA

Acute pulmonary toxicity following occupational exposure to a floor stain protector in the building industry in Switzerland.

International archives of occupational and environmental health. 2004;77(4):244-8

Centers for Disease Control and Prevention (CDC)

Acute respiratory illness linked to use of aerosol leather conditioner--Oregon, December 1992.

MMWR. Morbidity and mortality weekly report. 1993;41(52-53):965-7