The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.f

Cardiomyopathy (acute, subacute, chronic)

Publications

Ferreira PG, Costa S, Dias N, Ferreira AJ, Franco F

Simultaneous interstitial pneumonitis and cardiomyopathy induced by venlafaxine.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2014;40(3):313-8

Höjer J, Hulting J, Salmonson H

Fatal cardiotoxicity induced by venlafaxine overdosage.

Clinical toxicology (Philadelphia, Pa.). 2008;46(4):336-7

Drent M, Singh S, Gorgels AP, Hansell DM, Bekers O, Nicholson AG, van Suylen RJ, du Bois RM

Drug-induced pneumonitis and heart failure simultaneously associated with venlafaxine.

American journal of respiratory and critical care medicine. 2003;167(7):958-61

Partridge SJ, MacIver DH, Solanki T

A depressed myocardium.

Journal of toxicology. Clinical toxicology. 2000;38(4):453-5