The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.g

Cardiomyopathy (acute, subacute, chronic)

Publications

Ferreira PG, Costa S, Dias N, Ferreira AJ, Franco F

Simultaneous interstitial pneumonitis and cardiomyopathy induced by venlafaxine.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2014 May-Jun;40;313-8 — 2014 May-Jun — 313-8

Höjer J, Hulting J, Salmonson H

Fatal cardiotoxicity induced by venlafaxine overdosage.

Clinical toxicology (Philadelphia, Pa.) 2008 Apr;46;336-7 — 2008 Apr — 336-7

Drent M, Singh S, Gorgels AP, Hansell DM, Bekers O, Nicholson AG, van Suylen RJ, du Bois RM

Drug-induced pneumonitis and heart failure simultaneously associated with venlafaxine.

American journal of respiratory and critical care medicine 2003 Apr 01;167;958-61 — 2003 Apr 01 — 958-61

Partridge SJ, MacIver DH, Solanki T

A depressed myocardium.

Journal of toxicology. Clinical toxicology 2000;38;453-5 — 2000 — 453-5