The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.u

Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO

Publications

Lindeman E, Ålebring J, Johansson A, Ahlner J, Kugelberg FC, Nordmark Grass J

The unknown known: non-cardiogenic pulmonary edema in amlodipine poisoning, a cohort study.

Clinical toxicology (Philadelphia, Pa.) 2020 Mar 02;;1-8 — 2020 Mar 02 — 1-8

Ramanathan K, Mohanty B, Tang S, MacLaren G

Extracorporeal therapy for amlodipine poisoning.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2019 Sep 24;; — 2019 Sep 24