The Drug-Induced Respiratory Disease Website and App

XLIII. Airway involvement

XLIII.m Lolalized airway inflammation/burgeoning/stenosis: The pill aspiration syndrome

XLIII. Airway involvement

XLIII.p Thermal, chemical or caustic airway injury

XLIII. Airway involvement

XLIII.ai Bronchial stenosis/stricture

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.aw Chemical laryngitis

XLVII. Mediastinal involvement

XLVII.a Lymphadenopathy (intrathoracic)

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.e BAL: Stainable iron in macrophages

LVIII. Pathology

LVIII.ao Path: Localized/focal bronchiolitis

LVIII. Pathology

LVIII.aw Path: Tracheal or bronchial wall ulceration (see also IVs)

LVIII. Pathology

LVIII.cf Path: Stainable iron in airway wall (see also IVs)

XLIII. Airway involvement

XLIII.ab Cough (lone)

XLIII. Airway involvement

XLIII.ai Bronchial stenosis/stricture

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.c Upper airway obstruction other than angioedema or hematoma

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.i Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ac Large airway necrosis

LII. Esophageal involvement

LII.d Esophageal toxicity

LVIII. Pathology

LVIII.aw Path: Tracheal or bronchial wall ulceration (see also IVs)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.i Subclinical pulmonary infiltrates/ILD

I. Interstitial/parenchymal lung disease

I.p Focal/localized area of pneumonitis/fibrosis

I. Interstitial/parenchymal lung disease

I.w Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

I. Interstitial/parenchymal lung disease

I.y Pleuroparenchymal fibroelastosis (PPFE)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLIII. Airway involvement

XLIII.j Bronchiectasis

XLIII. Airway involvement

XLIII.ai Bronchial stenosis/stricture

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.c Upper airway obstruction other than angioedema or hematoma

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.d Laryngeal disorder-Laryngeal nerve palsy (dysphonia, hoarseness)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.g Vocal cord paresis/paralysis

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.s Tracheal/large airway necrosis, chondronecrosis, perforation

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.aa Pseudomembranous tracheitis/tracheobronchitis

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ab Airway (e.g. tracheoesophageal) fistula

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ac Large airway necrosis

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.b Eosinophilic pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.c Pleural thickening - Fibrothorax

XLV. Pleural and/or pericardial involvement

XLV.f Pneumothorax

XLV. Pleural and/or pericardial involvement

XLV.h Chylothorax

XLV. Pleural and/or pericardial involvement

XLV.l Malignant pleural mesothelioma

XLV. Pleural and/or pericardial involvement

XLV.m Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

XLV. Pleural and/or pericardial involvement

XLV.u The apical cap

XLVI. Pulmonary vasculopathy

XLVI.c Pulmonary veno-occlusive disease

XLVI. Pulmonary vasculopathy

XLVI.r Pulmonary artery aneurysm(s)

XLVI. Pulmonary vasculopathy

XLVI.aa Pulmonary artery stenosis

XLVII. Mediastinal involvement

XLVII.d Fibrosing mediastinitis

XLVII. Mediastinal involvement

XLVII.i Mediastinitis

XLVII. Mediastinal involvement

XLVII.j Compression of mediastinal structures/organs

XLVII. Mediastinal involvement

XLVII.l Calcification of mediastinal lymph nodes

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.a Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.aj Paraspinal muscle myositis/myopathy/neuromyopathy +- the dropped head syndrome

L. Miscellaneous

L.h Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

L. Miscellaneous

L.m Chest deformity: platythorax

L. Miscellaneous

L.s Rib fracture

L. Miscellaneous

L.ad Vertebral compression fracture

L. Miscellaneous

L.bc Aorto-esophageal fistula

L. Miscellaneous

L.bn Dropped-head syndrome

LI. Cardiovascular involvement / toxicity

LI.a Left or biventricular dysfunction/failure

LI. Cardiovascular involvement / toxicity

LI.b Valvular heart disease and/or dysfunction

LI. Cardiovascular involvement / toxicity

LI.g Cardiomyopathy (acute, subacute, chronic)

LI. Cardiovascular involvement / toxicity

LI.h Coronary artery disease (acute) - Myocardial ischemia/infarction

LI. Cardiovascular involvement / toxicity

LI.l Constrictive pericarditis - Pericardial thickening

LI. Cardiovascular involvement / toxicity

LI.p Coronary artery disease (subacute, chronic)

LI. Cardiovascular involvement / toxicity

LI.t Heart block (bundle branch- or AV-)

LI. Cardiovascular involvement / toxicity

LI.af Effusive-constrictive pericarditis

LI. Cardiovascular involvement / toxicity

LI.am Late left ventricular dysfunction/failure

LI. Cardiovascular involvement / toxicity

LI.ap Pericardial calcification

LI. Cardiovascular involvement / toxicity

LI.bf Coarctation of the aorta (acquired)

LI. Cardiovascular involvement / toxicity

LI.bx Aortoesophageal fistula

LII. Esophageal involvement

LII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

LII. Esophageal involvement

LII.c Esophageal stenosis/stricture

LII. Esophageal involvement

LII.d Esophageal toxicity

LV. Imaging

LV.ac Imaging: Cavitating/cavitary lung nodule, mass or nodules (see also Iq, XIs, XIIi, XVIaa and XVIIp)

LV. Imaging

LV.bm Imaging: Hyperlucent lung

LV. Imaging

LV.bn Imaging: Atelectasis (a combination of increased density and volume loss. Typically lobar)

LV. Imaging

LV.bp Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

LVIII. Pathology

LVIII.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

LVIII. Pathology

LVIII.x Path: Pulmonary fibrosis (not otherwise specified or unclassifiable)

LX. Neoplastic conditions

LX.a Lung cancer

LX. Neoplastic conditions

LX.d Malignant mesothelioma (pleural, pericardial)

LX. Neoplastic conditions

LX.e Breast cancer

LX. Neoplastic conditions

LX.j Pulmonary synovial sarcoma

LX. Neoplastic conditions

LX.l Chondrosarcoma

LX. Neoplastic conditions

LX.m Tumor of the heart

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.i Subclinical pulmonary infiltrates/ILD

I. Interstitial/parenchymal lung disease

I.l Lung nodule or nodules

I. Interstitial/parenchymal lung disease

I.m Diffuse alveolar damage (DAD) (see alsoo under IIb and XVf)

I. Interstitial/parenchymal lung disease

I.p Focal/localized area of pneumonitis/fibrosis

I. Interstitial/parenchymal lung disease

I.w Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

I. Interstitial/parenchymal lung disease

I.y Pleuroparenchymal fibroelastosis (PPFE)

I. Interstitial/parenchymal lung disease

I.z Progression, acceleration or exacerbation of preexisting ILD/fibrosis

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.h Major/massive hemoptysis

XLIII. Airway involvement

XLIII.ai Bronchial stenosis/stricture

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.c Upper airway obstruction other than angioedema or hematoma

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.g Vocal cord paresis/paralysis

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.s Tracheal/large airway necrosis, chondronecrosis, perforation

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ab Airway (e.g. tracheoesophageal) fistula

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ac Large airway necrosis

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.c Pleural thickening - Fibrothorax

XLV. Pleural and/or pericardial involvement

XLV.f Pneumothorax

XLV. Pleural and/or pericardial involvement

XLV.h Chylothorax

XLV. Pleural and/or pericardial involvement

XLV.k Pleural calcifications

XLVI. Pulmonary vasculopathy

XLVI.c Pulmonary veno-occlusive disease

XLVI. Pulmonary vasculopathy

XLVI.w Pulmonary lymphangiectasis

XLVII. Mediastinal involvement

XLVII.d Fibrosing mediastinitis

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.j Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.t Cavitation/necrosis of lung tumor or metastases

L. Miscellaneous

L.ad Vertebral compression fracture

LI. Cardiovascular involvement / toxicity

LI.b Valvular heart disease and/or dysfunction

LI. Cardiovascular involvement / toxicity

LI.l Constrictive pericarditis - Pericardial thickening

LI. Cardiovascular involvement / toxicity

LI.p Coronary artery disease (subacute, chronic)

LI. Cardiovascular involvement / toxicity

LI.t Heart block (bundle branch- or AV-)

LII. Esophageal involvement

LII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

LII. Esophageal involvement

LII.d Esophageal toxicity

LII. Esophageal involvement

LII.e Esophageal dysmotility

LV. Imaging

LV.bp Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.a BAL: An excess proportion of lymphocytes

LVIII. Pathology

LVIII.d Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

LVIII. Pathology

LVIII.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

LVIII. Pathology

LVIII.q Path: Pneumocyte atypia (reactive epithelial cells) (a.k.a. the "Napoleon Hat" sign)

LVIII. Pathology

LVIII.v Path: NSIP-fibrotic pattern

LVIII. Pathology

LVIII.cg Path: Diffuse lymphangiectasis

LIX. Infections & related conditions

LIX.e Pneumocystis jiroveci pneumonia

LIX. Infections & related conditions

LIX.ae Reactivation of a prior pulmonary infection (TB, melioidosis)

LX. Neoplastic conditions

LX.e Breast cancer

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.f Acute fibrinous organizing pneumonia (AFOP)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.o Pulmonary alveolar proteinosis (PAP)

I. Interstitial/parenchymal lung disease

I.w Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

I. Interstitial/parenchymal lung disease

I.y Pleuroparenchymal fibroelastosis (PPFE)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.a Pulmonary edema, noncardiogenic (NCPE)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.g Transfusion-related acute lung injury (TRALI) (May cause ARDS)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.o Engraftment syndrome

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLIII. Airway involvement

XLIII.x Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

XLIII. Airway involvement

XLIII.ai Bronchial stenosis/stricture

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.aa Pseudomembranous tracheitis/tracheobronchitis

XLV. Pleural and/or pericardial involvement

XLV.f Pneumothorax

XLVI. Pulmonary vasculopathy

XLVI.b Pulmonary arterial hypertension

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.c Capillary leak syndrome (CLS)

LI. Cardiovascular involvement / toxicity

LI.a Left or biventricular dysfunction/failure

LV. Imaging

LV.w Imaging: Lung nodule or nodules

LVIII. Pathology

LVIII.a Path: NSIP-cellular pattern (see also Ia, Ib)

LVIII. Pathology

LVIII.d Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

LVIII. Pathology

LVIII.e Path: Acute fibrinous organizing pneumonia (AFOP-pattern) (see also If)

LVIII. Pathology

LVIII.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

LVIII. Pathology

LVIII.r Path: Alveolar hemorrhage (see also IIIa)

LVIII. Pathology

LVIII.aq Path: Obliterative (constrictive) bronchiolitis (see also IVc, IVn)

LVIII. Pathology

LVIII.bd Path: Pulmonary veno-occlusive disease (PVOD)

LVIII. Pathology

LVIII.bf Path: Pulmonary cytolytic thrombi

LVIII. Pathology

LVIII.br Path: Pleuroparenchymal fibrosis/fibroelastosis (PPFE)

LIX. Infections & related conditions

LIX.m Fungal airway infection

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.u Pneumoconiosis (silicosis, talcosis...)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.h Hypoxemia, low oxygen saturation (may occur in isolation)

XLIII. Airway involvement

XLIII.x Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

XLIII. Airway involvement

XLIII.z Foreign body aspiration bronchiolitis

XLIII. Airway involvement

XLIII.ai Bronchial stenosis/stricture

XLV. Pleural and/or pericardial involvement

XLV.c Pleural thickening - Fibrothorax

XLV. Pleural and/or pericardial involvement

XLV.s Pleural mass or masses

XLVI. Pulmonary vasculopathy

XLVI.b Pulmonary arterial hypertension

XLVI. Pulmonary vasculopathy

XLVI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

XLVII. Mediastinal involvement

XLVII.f An enlarged or dense thymus

XLVII. Mediastinal involvement

XLVII.n Mediastinal talcoma

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.r Chest pressure/discomfort

LV. Imaging

LV.w Imaging: Lung nodule or nodules

LV. Imaging

LV.ag Imaging: A pattern similar to pneumoconiotic progressive massive fibrosis (PMF)

LV. Imaging

LV.bj Imaging: Avid pleural uptake on PET-scan

LVI. Distinctive patterns - 'Eye-catchers'

LVI.i Eye-catcher: Tracer-avid pleural area or areas on PET-CT

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.k BAL: Talc crystals in macrophages or lying free in BALF

LVIII. Pathology

LVIII.f Path: ILD with a granulomatous component (see also Im)

LVIII. Pathology

LVIII.ab Path: Foreign body deposits/granulomatous reaction

LVIII. Pathology

LVIII.ac Path: Pneumoconiosis (silicosis, talcosis, talcoma)

LVIII. Pathology

LVIII.an Path: Foreign body embolism, microangiopathy, vasculopathy

LVIII. Pathology

LVIII.dd Path: Birefringent particles in lung tissue and/or cells