The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Left or biventricular dysfunction/failure
Publications
Extensive radiation-induced heart disease in an adult patient treated for lymphoma as a child.
The Canadian journal of cardiology 2011 May-Jun;27;390.e1-4 — 2011 May-Jun — 390.e1-4
Pathology of radiation-induced heart disease: a surgical and autopsy study of 27 cases.
Human pathology 1996 Aug;27;766-73 — 1996 Aug — 766-73