The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Aorto-esophageal fistula
Publications
Radiation-induced aortoesophageal fistula: an unusual case of massive upper gastrointestinal bleeding.
The Journal of emergency medicine 2002 Aug;23;175-8 — 2002 Aug — 175-8
Fatal hemorrhage complicating carcinoma of the esophagus. Report of four cases.
The American journal of gastroenterology 1976 May;65;422-6 — 1976 May — 422-6