The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pneumothorax
Publications
Complications of attempted central venous injections performed by drug abusers.
Chest 1980 Oct;78;613-7 — 1980 Oct — 613-7
Spontaneous pneumothorax following thoracic irradiation.
Chest 1985 Nov;88;703-8 — 1985 Nov — 703-8
Recurrent spontaneous pneumothorax after radiation therapy to the thorax.
Chest 1978 Mar;73;387-8 — 1978 Mar — 387-8