The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Coronary artery disease (acute) - Myocardial ischemia/infarction
Review at 24092234
Publications
How to prevent and manage radiation-induced coronary artery disease.
Heart (British Cardiac Society) 2018 10;104;1647-1653 — 2018 10 — 1647-1653
Dosimetric Correlate of Cardiac-Specific Survival Among Patients Undergoing Coronary Artery Stenting After Thoracic Radiotherapy for Cancer.
American journal of clinical oncology 2017 Apr;40;133-139 — 2017 Apr — 133-139
Case records of the Massachusetts General Hospital. Case 24-2010. A 56-year-old woman with a history of Hodgkin's lymphoma and sudden onset of dyspnea and shock.
The New England journal of medicine 2010 Aug 12;363;664-75 — 2010 Aug 12 — 664-75
Baker JE, Fish BL, Su J, Haworth ST, Strande JL, Komorowski RA, Migrino RQ, Doppalapudi A, Harmann L, Allen Li X, Hopewell JW, Moulder JE
10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model.
International journal of radiation biology 2009 Dec;85;1089-100 — 2009 Dec — 1089-100