The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pulmonary arterial hypertension
Publications
Nakaoka H, Sakata Y, Yamamoto M, Maeda T, Arita Y, Shioyama W, Nakaoka Y, Kanakura Y, Yamashita S, Komuro I, Yamauchi-Takihara K
Pulmonary hypertension associated with bone marrow transplantation.
Journal of cardiology cases 2010 Aug;2;e23-e27 — 2010 Aug — e23-e27
Pulmonary arterial hypertension in pediatric patients with hematopoietic stem cell transplant-associated thrombotic microangiopathy.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2013 Feb;19;202-7 — 2013 Feb — 202-7
Steward CG, Pellier I, Mahajan A, Ashworth MT, Stuart AG, Fasth A, Lang D, Fischer A, Friedrich W, Schulz AS,
Severe pulmonary hypertension: a frequent complication of stem cell transplantation for malignant infantile osteopetrosis.
British journal of haematology 2004 Jan;124;63-71 — 2004 Jan — 63-71