The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VIII.d

Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

Publications

Küpeli E, Khemasuwan D, Lee P, Mehta AC

"Pills" and the air passages.

Chest. 2013;144(2):651-660

Kinsey CM, Folch E, Majid A, Channick CL

Evaluation and management of pill aspiration: case discussion and review of the literature.

Chest. 2013;143(6):1791-1795

Grosu HB, Jimenez CA, Eapen GA, Ost D, Moran C, Morice RC

The iron lady.

American journal of respiratory and critical care medicine. 2012;186(5):460

Lee P, Culver DA, Farver C, Mehta AC

Syndrome of iron pill aspiration.

Chest. 2002;121(4):1355-7