The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.e

Organizing pneumonia pattern (an area or areas of consolidation on imaging)

Publications

Oie Y, Saito Y, Kato M, Ito F, Hattori H, Toyama H, Kobayashi H, Katada K

Relationship between radiation pneumonitis and organizing pneumonia after radiotherapy for breast cancer.

Radiation oncology (London, England) 2013 Mar 08;8;56 — 2013 Mar 08 — 56

Majori M, Poletti V, Curti A, Corradi M, Falcone F, Pesci A

Bronchoalveolar lavage in bronchiolitis obliterans organizing pneumonia primed by radiation therapy to the breast.

The Journal of allergy and clinical immunology 2000 Feb;105;239-44 — 2000 Feb — 239-44

Bayle JY, Nesme P, Béjui-Thivolet F, Loire R, Guérin JC, Cordier JF

Migratory organizing pneumonitis "primed" by radiation therapy.

The European respiratory journal 1995 Feb;8;322-6 — 1995 Feb — 322-6

Crestani B, Kambouchner M, Soler P, Crequit J, Brauner M, Battesti JP, Valeyre D

Migratory bronchiolitis obliterans organizing pneumonia after unilateral radiation therapy for breast carcinoma.

The European respiratory journal 1995 Feb;8;318-21 — 1995 Feb — 318-21