The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Malignant mesothelioma (pleural, pericardial)
In a series of 22 patients (PMID 24248693) radiation-lymphoma-associated mesothelioma were younger, more likely to have unusual histologic features, had lower asbsetos body counts and had a longer overall survival compared with patients with asbestos-associated mesothelioma
Publications
Post-irradiation pericardial malignant mesothelioma with deletion of p16: a case report.
Cancer biology & medicine 2018 Feb;15;97-102 — 2018 Feb — 97-102
Chirieac LR, Barletta JA, Yeap BY, Richards WG, Tilleman T, Bueno R, Baldini EH, Godleski J, Sugarbaker DJ
Clinicopathologic characteristics of malignant mesotheliomas arising in patients with a history of radiation for Hodgkin and non-Hodgkin lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013 Dec 20;31;4544-9 — 2013 Dec 20 — 4544-9
Camiade E, Gramond C, Jutand MA, Audignon S, Rinaldo M, Imbernon E, Luce D, Galateau-Sallé F, Astoul P, Pairon JC, Brochard P, Lacourt A
Characterization of a French series of female cases of mesothelioma.
American journal of industrial medicine 2013 Nov;56;1307-16 — 2013 Nov — 1307-16
De Bruin ML, Burgers JA, Baas P, van 't Veer MB, Noordijk EM, Louwman MW, Zijlstra JM, van den Berg H, Aleman BM, van Leeuwen FE
Malignant mesothelioma after radiation treatment for Hodgkin lymphoma.
Blood 2009 Apr 16;113;3679-81 — 2009 Apr 16 — 3679-81