The Drug-Induced Respiratory Disease Website and App

Status post-hematopoietic stem cell (HSCT) or bone marrow transplantation (BMT)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.e

Transfusion-related acute lung injury (TRALI) (May cause ARDS)

Publications

Silliman CC, McLaughlin NJ

Transfusion-related acute lung injury.

Blood reviews. 2006;20(3):139-59

Ganguly S, Carrum G, Nizzi F, Heslop HE, Popat U

Transfusion-related acute lung injury (TRALI) following allogeneic stem cell transplant for acute myeloid leukemia.

American journal of hematology. 2004;75(1):48-51

Urahama N, Tanosaki R, Masahiro K, Iijima K, Chizuka A, Kim SW, Hori A, Kojima R, Imataki O, Makimito A, Mineishi S, Takaue Y

TRALI after the infusion of marrow cells in a patient with acute lymphoblastic leukemia.

Transfusion. 2003;43(11):1553-7