The Drug-Induced Respiratory Disease Website and App

Radiation therapy (medium term & late effects)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VIII.ab

Airway (e.g. tracheoesophageal) fistula

Publications

Ota T, Suzumura T, Sugiura T, Hasegawa Y, Yonesaka K, Makihara M, Tsukuda H, Tada T, Fukuoka M

Spontaneous pneumothorax due to bronchopleural fistula following reirradiation for locoregionally recurrent squamous cell lung cancer.

Clinical case reports. 2016;4(5):481-5

Franquet T, Giménez A, Rosón N, Torrubia S, Sabaté JM, Pérez C

Aspiration diseases: findings, pitfalls, and differential diagnosis.

Radiographics : a review publication of the Radiological Society of North America, Inc. 2000;20(3):673-85