The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Cardiomyopathy (acute, subacute, chronic)
Review at 24092234
Publications
Treatment-related cardiotoxicity in survivors of childhood cancer.
Nature reviews. Clinical oncology. 2013;10(12):697-710
Pathology of radiation-induced heart disease: a surgical and autopsy study of 27 cases.
Human pathology. 1996;27(8):766-73
Radiation therapy-induced cardiac injury.
American heart journal. 1995;129(6):1193-6