The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

III.h

Major/massive hemoptysis

Publications

Karam SD, Horne ZD, Hong RL, McRae D, Duhamel D, Nasr NM

Dose escalation with stereotactic body radiation therapy boost for locally advanced non small cell lung cancer.

Radiation oncology (London, England) 2013 Jul 10;8;179 — 2013 Jul 10 — 179

Mehta AC, Dweik RA

Necrosis of the bronchus. Role of radiation.

Chest 1995 Nov;108;1462-6 — 1995 Nov — 1462-6