The Drug-Induced Respiratory Disease Website and App

Status post-hematopoietic stem cell (HSCT) or bone marrow transplantation (BMT)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.v

Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

Publications

Madanat-Harjuoja LM, Valjento S, Vettenranta K, Kajosaari M, Dyba T, Taskinen M

Pulmonary function following allogeneic stem cell transplantation in childhood: a retrospective cohort study of 51 patients.

Pediatric transplantation. 2014;18(6):617-24

Moermans C, Poulet C, Henket M, Bonnet C, Willems E, Baron F, Beguin Y, Louis R

Lung function and airway inflammation monitoring after hematopoietic stem cell transplantation.

Respiratory medicine. 2013;107(12):2071-80