The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.p

Thermal, chemical or caustic airway injury

Publications

Bueno-Sacristán D, Pintado B, Durán-Barata D, Navarro-Cantero A, Mirambeaux RM, Palacios J, Barrios D, Benito A

Acute Dyspnea and Hemoptysis in an 84-Year-Old Man With Multiple Comorbidities.

Chest 2022 02;161;e97-e101 — 2022 02 — e97-e101

Keshishyan S, Mohan A, Ahmed S, Dhillon SS, Patil M, Harris K

Airway Obstruction Caused by Iron Pill Aspiration: An Interventional Pulmonology Approach to Prevent Surgery.

Heart, lung & circulation 2018 Aug;27;e89-e92 — 2018 Aug — e89-e92

Clarke BE, Kim ST

Iron-induced bronchial injury.

Histopathology 2002 Nov;41;472-3 — 2002 Nov — 472-3