The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Large airway necrosis
Publications
Bronchoscopic Manifestations of Airway Toxicity After Radiotherapy.
Clinical lung cancer 2018 11;19;e875-e878 — 2018 11 — e875-e878
Radiation-associated airway necrosis.
The Ochsner journal 2013;13;273-5 — 2013 — 273-5
Posttreatment CT and MR imaging in head and neck cancer: what the radiologist needs to know.
Radiographics : a review publication of the Radiological Society of North America, Inc 2012 Sep-Oct;32;1261-82; discussion 1282-4 — 2012 Sep-Oct — 1261-82; discussion 1282-4
Necrosis of the bronchus. Role of radiation.
Chest 1995 Nov;108;1462-6 — 1995 Nov — 1462-6