The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Heart block (bundle branch- or AV-)
Publications
Báez-Ferrer N, Izquierdo-Gómez MM, Beyello-Belkasem C, Jorge-Pérez P, García-González MJ, Ferrer-Hita JJ, De la Rosa-Hernández A, García-Niebla J, Lacalzada-Almeida J
Long-Term Radiotherapy-Induced Cardiac Complications: A Case Report.
The American journal of case reports 2019 Aug 11;20;1182-1188 — 2019 Aug 11 — 1182-1188
Slama MS, Le Guludec D, Sebag C, Leenhardt AR, Davy JM, Pellerin DE, Drieu LH, Victor J, Brechenmacher C, Motté G
Complete atrioventricular block following mediastinal irradiation: a report of six cases.
Pacing and clinical electrophysiology : PACE 1991 Jul;14;1112-8 — 1991 Jul — 1112-8