The Drug-Induced Respiratory Disease Website and App

Radiation therapy (medium term & late effects)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVI.c

Pulmonary veno-occlusive disease

Publications

Kramer MR, Estenne M, Berkman N, Antoine M, de Francquen P, Lipski A, Jacobovitz D, Lafair J

Radiation-induced pulmonary veno-occlusive disease.

Chest 1993 Oct;104;1282-4 — 1993 Oct — 1282-4

Lombard CM, Churg A, Winokur S

Pulmonary veno-occlusive disease following therapy for malignant neoplasms.

Chest 1987 Nov;92;871-6 — 1987 Nov — 871-6