The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Bronchial stenosis/stricture
Publications
Bronchoscopic Manifestations of Airway Toxicity After Radiotherapy.
Clinical lung cancer 2018 11;19;e875-e878 — 2018 11 — e875-e878
Fibrotic airway stenosis following radiotherapy in patients with adenoid cystic carcinoma.
Respirology (Carlton, Vic.) 2014 Aug;19;914-20 — 2014 Aug — 914-20
Miller KL, Shafman TD, Anscher MS, Zhou SM, Clough RW, Garst JL, Crawford J, Rosenman J, Socinski MA, Blackstock W, Sibley GS, Marks LB
Bronchial stenosis: an underreported complication of high-dose external beam radiotherapy for lung cancer?
International journal of radiation oncology, biology, physics 2005 Jan 01;61;64-9 — 2005 Jan 01 — 64-9
Radiation-induced bronchial stenosis: a new cause of platypnea-orthodeoxia.
Southern medical journal 1999 Jul;92;720-4 — 1999 Jul — 720-4
Bronchial stenosis and sclerosing mediastinitis: an uncommon complication of external thoracic radiotherapy.
The European respiratory journal 1998 May;11;1188-90 — 1998 May — 1188-90