The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIV.ac

Large airway necrosis

Publications

Duijm M, Schillemans W, Aerts JG, Heijmen B, Nuyttens JJ

Dose and Volume of the Irradiated Main Bronchi and Related Side Effects in the Treatment of Central Lung Tumors With Stereotactic Radiotherapy.

Seminars in radiation oncology 2016 Apr;26;140-8 — 2016 Apr — 140-8

Alraiyes AH, Alraies MC, Abbas A

Radiation-associated airway necrosis.

The Ochsner journal 2013;13;273-5 — 2013 — 273-5

Corradetti MN, Haas AR, Rengan R

Central-airway necrosis after stereotactic body-radiation therapy.

The New England journal of medicine 2012 Jun 14;366;2327-9 — 2012 Jun 14 — 2327-9

Mehta AC, Dweik RA

Necrosis of the bronchus. Role of radiation.

Chest 1995 Nov;108;1462-6 — 1995 Nov — 1462-6