Philippe Camus, M.D.

Dijon, France

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X.af

X - Systemic/Distant conditions, syndromes and reactions

Skin purpura, ecchymoses or necrosis

Last update 17/06/2026

As the result of vasculopathy which can be occlusive and/or vasculitic, causing retiform purpura, painful violaceous plaques and skin necrosis which can be extensive. The lesions have a predilection to localize in the ear lobes, face and limbs, causing extensive damage. Extensive skin necrosis raises management issues similar to that in burned patients. Concomitant DAH is a possibility

Causative drugs

5

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)
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