The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Nasal, palatal and/or pharyngeal pathology

Publications

Ruffer N, Krusche M, Holl-Ulrich K, Kötter I, Lötscher F

[Cocaine-induced vasculitis and mimics of vasculitis].

Zeitschrift fur Rheumatologie 2023 Sep;82;606-614 — 2023 Sep — 606-614

Hussaini AS, Black CK, Malekzadeh S, Milmoe GJ

Extensive Sinonasal and Oropharyngeal Necrosis as a Consequence of Adulterated Cocaine with Mimicry of ANCA-Positive Vasculitis.

OTO open 2019 Oct-Dec;3;2473974X19894239 — 2019 Oct-Dec — 2473974X19894239