The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.u

Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

Pathophysiology at PMID 27354687

Publications

Kötter I, Reinhold-Keller E

[Vasculitis mimics].

Zeitschrift fur Rheumatologie 2019 Feb;78;24-30 — 2019 Feb — 24-30

Jin Q, Kant S, Alhariri J, Geetha D

Levamisole adulterated cocaine associated ANCA vasculitis: review of literature and update on pathogenesis.

Journal of community hospital internal medicine perspectives 2018;8;339-344 — 2018 — 339-344

Aoun B, Alali M, Degheili JA, Sanjad S, Vaquin C, Donadieu J, Ulinski T, Termos S

Distinctive vasculopathy with systemic involvement due to levamisole long-term therapy: a case report.

Journal of medical case reports 2018 Jul 16;12;209 — 2018 Jul 16 — 209

Garg L, Gupta S, Swami A, Zhang P

Levamisole/Cocaine Induced Systemic Vasculitis and Immune Complex Glomerulonephritis.

Case reports in nephrology 2015;2015;372413 — 2015 — 372413

Lemaignen A, Goulenok T, Kalamarides S, Plat A, Pfau G, Fantin B

[Agranulocytosis and vasculitis in a cocaine addict: levamisole, the hidden culprit].

La Revue de medecine interne 2014 Oct;35;676-9 — 2014 Oct — 676-9

Strazzula L, Brown KK, Brieva JC, Camp BJ, Frankel HC, Kissin E, Mahlberg MJ, Mina MA, Pomeranz MK, Brownell I, Kroshinsky D

Levamisole toxicity mimicking autoimmune disease.

Journal of the American Academy of Dermatology 2013 Dec;69;954-9 — 2013 Dec — 954-9

Carter MR, Amirhaeri S

p-ANCA-Associated Vasculitis Caused by Levamisole-Adulterated Cocaine: A Case Report.

Case reports in emergency medicine 2013;2013;878903 — 2013 — 878903

Arora NP

Cutaneous vasculopathy and neutropenia associated with levamisole-adulterated cocaine.

The American journal of the medical sciences 2013 Jan;345;45-51 — 2013 Jan — 45-51

Graf J

Rheumatic manifestations of cocaine use.

Current opinion in rheumatology 2013 Jan;25;50-5 — 2013 Jan — 50-5

Kopp SA, High WA, Green JJ

Levamisole-induced Wegener's granulomatosis following contaminated cocaine abuse.

Skinmed 2012 Jul-Aug;10;254-6 — 2012 Jul-Aug — 254-6

McGrath MM, Isakova T, Rennke HG, Mottola AM, Laliberte KA, Niles JL

Contaminated cocaine and antineutrophil cytoplasmic antibody-associated disease.

Clinical journal of the American Society of Nephrology : CJASN 2011 Dec;6;2799-805 — 2011 Dec — 2799-805

Barbano G, Ginevri F, Ghiggeri GM, Gusmano R

Disseminated autoimmune disease during levamisole treatment of nephrotic syndrome.

Pediatric nephrology (Berlin, Germany) 1999 Sep;13;602-3 — 1999 Sep — 602-3