The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Dual MPO-/PR3-ANCA systemic disease/vasculitis/pseudovasculitis
Publications
Unusual case of levamisole-induced dual-positive ANCA vasculitis and crescentic glomerulonephritis.
BMJ case reports. 2018;2018
Cocaine/levamisole-associated autoimmune syndrome: a disease of neutrophil-mediated autoimmunity.
Current opinion in hematology. 2018;25(1):29-36
Cocaine and ANCA associated vasculitis-like syndromes - A case series.
Autoimmunity reviews. 2018;17(1):73-77
A Case Report on Suspected Levamisole-Induced Pseudovasculitis.
WMJ : official publication of the State Medical Society of Wisconsin. 2017;116(1):37-9
Veronese FV, Dode RS, Friderichs M, Thomé GG, da Silva DR, Schaefer PG, Sebben VC, Nicolella AR, Barros EJ
Cocaine/levamisole-induced systemic vasculitis with retiform purpura and pauci-immune glomerulonephritis.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 2016;49(5):e5244
Levamisole-contaminated cocaine: a hairy affair.
BMJ case reports. 2015;2015
Trojan horses: drug culprits associated with antineutrophil cytoplasmic autoantibody (ANCA) vasculitis.
Current opinion in rheumatology. 2014;26(1):42-9