Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.o

Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

Circulating ANCAs are found in most cases

Publications

Miner J, Gruber P, Perry TL

Early excision and grafting, an alternative approach to the surgical management of large body surface area levamisole-adulterated cocaine induced skin necrosis.

Burns : journal of the International Society for Burn Injuries 2015 May;41;e34-40 — 2015 May — e34-40

Ferlazzo B, Barresi G, Puglisi A

[Cutaneous necrotizing vasculitis caused by immunocomplexes during treatment with levamisole].

Bollettino dell'Istituto sieroterapico milanese 1983 Mar 31;62;107-11 — 1983 Mar 31 — 107-11

Macfarlane DG, Bacon PA

Levamisole-induced vasculitis due to circulating immune complexes.

British medical journal 1978 Feb 18;1;407-8 — 1978 Feb 18 — 407-8