The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)
Circulating ANCAs are found in most cases
Publications
Early excision and grafting, an alternative approach to the surgical management of large body surface area levamisole-adulterated cocaine induced skin necrosis.
Burns : journal of the International Society for Burn Injuries. 2015;41(3):e34-40
[Cutaneous necrotizing vasculitis caused by immunocomplexes during treatment with levamisole].
Bollettino dell'Istituto sieroterapico milanese. 1983;62(1):107-11
Levamisole-induced vasculitis due to circulating immune complexes.
British medical journal. 1978;1(6110):407-8