The Drug-Induced Respiratory Disease Website and App

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.y Progression, acceleration or exacerbation of preexisting ILD/fibrosis

I. Interstitial/parenchymal lung disease

I.ao Pulmonary infiltrates

II. Pulmonary edema - Acute lung injury - ARDS

II.b ARDS - Acute lung injury

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.c Hemoptysis

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.h Major/massive hemoptysis

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.l Alveolar hemorrhage, localized (e.g. lobar)

IV. Airway involvement

IV.d Cough (lone)

IV. Airway involvement

IV.z Bronchial wall erosion/hematoma

IV. Airway involvement

IV.ah Bronchopericardial fistula

V. Pleural and/or pericardial involvement

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

V. Pleural and/or pericardial involvement

V.e Hemothorax - Serosanguineous pleural effusion

V. Pleural and/or pericardial involvement

V.n Hemopericardium - Bloody pericardial effusion

VI. Pulmonary vasculopathy

VI.b Pulmonary arterial hypertension

VI. Pulmonary vasculopathy

VI.o Air/gas embolism

VI. Pulmonary vasculopathy

VI.z Pulmonary vein stenosis

VI. Pulmonary vasculopathy

VI.ac Pulmonary infarction

VI. Pulmonary vasculopathy

VI.ae Pulmonary vein perforation/rupture

VII. Mediastinal involvement

VII.d Fibrosing mediastinitis

VII. Mediastinal involvement

VII.g Hemomediastinum - Mediastinal hematoma

VII. Mediastinal involvement

VII.h Pneumomediastinum

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.b Hematoma of/around central airway wall potentially causing UAO

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.h Vocal cord dysfunction, adduction, closure, injury

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.j Laryngeal disorder-Laryngeal nerve palsy (dysphonia, hoarseness)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.j Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.n Vagal nerve injury (may cause GE reflux/GERD)

XI. Miscellaneous

XI.b Chest pain (acute or subacute), lone or prominent

XI. Miscellaneous

XI.k Esophageal hematoma (may cause chest pain and/or tracheal compression)

XII. Cardiovascular involvement / toxicity

XII.c Pericardial effusion (w/wo tamponade)

XII. Cardiovascular involvement / toxicity

XII.g Coronary artery disease (acute) - Myocardial ischemia/infarction

XII. Cardiovascular involvement / toxicity

XII.y Pneumopericardium

XII. Cardiovascular involvement / toxicity

XII.af Coronary vasospasm - Vasospastic angina

XII. Cardiovascular involvement / toxicity

XII.aw Postcardiac/-cardiotomy injury (PCIS-Dressler syndrome)

XII. Cardiovascular involvement / toxicity

XII.bd Perforation of the heart - Cardiac rupture

XII. Cardiovascular involvement / toxicity

XII.bg Atrio-esophageal fistula

XII. Cardiovascular involvement / toxicity

XII.bh Atrial septal defect, acquired

XII. Cardiovascular involvement / toxicity

XII.bk Pulmonary vein thrombosis

XII. Cardiovascular involvement / toxicity

XII.cb Pericardial-esophageal fistula

XV. Pathology

XV.g Path: Alveolar hemorrhage (see also IIIa)

XV. Pathology

XV.ah Path: Pulmonary congestion

XV. Pathology

XV.ak Path: Pulmonary veno-occlusive disease (PVOD)

XV. Pathology

XV.cx Path: Pulmonary vein stenosis

XVI. Imaging

XVI.b Imaging: Ground-glass opacities (GGO) / shadowing

XVI. Imaging

XVI.l Imaging: Peribronchovascular areas of consolidation

XVI. Imaging

XVI.bg Imaging: Pulmonary vein stenosis

XVI. Imaging

XVI.bo Imaging: Localized calcification of pulmonary vein or veins

XVII. Infections & related conditions

XVII.a Respiratory tract infection incl. pneumonia

XXVII. Esophageal involvement

XXVII.a Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.j Exogenous lipoid pneumonia (subacute, acute)

I. Interstitial/parenchymal lung disease

I.af Chemical (toxic) pneumonitis

II. Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

II. Pulmonary edema - Acute lung injury - ARDS

II.b ARDS - Acute lung injury

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.b Pneumorenal syndrome (w/wo ANCAs)

IV. Airway involvement

IV.c Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

IV. Airway involvement

IV.n Obstructive airway dysfunction (see also IVc, XVx)

IV. Airway involvement

IV.q Reactive airway dysfunction syndrome (RADS)

V. Pleural and/or pericardial involvement

V.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.c Upper airway obstruction other than angioedema or hematoma

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.h Vocal cord dysfunction, adduction, closure, injury

X. Systemic/Distant conditions, syndromes and reactions

X.m Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

X. Systemic/Distant conditions, syndromes and reactions

X.u Multiple organ dysfunction/failure (MODS/MOF)

X. Systemic/Distant conditions, syndromes and reactions

X.ac Anti-GBM antibody disease (Goodpasture-like or flare of preexisting GS)

XI. Miscellaneous

XI.s Sniffing death - Death from inhalation of compound

XII. Cardiovascular involvement / toxicity

XII.m Cardiac- cardiorespiratory/pulmonary arrest

XIV. Hemoglobinopathies - Abnormal hemoglobin states (acquired)

XIV.a Methemoglobinemia

XIV. Hemoglobinopathies - Abnormal hemoglobin states (acquired)

XIV.b Sulfhemoglobinemia

XV. Pathology

XV.x Path: Acute/subacute bronchiolitis (see also IVc, IVi)

XVI. Imaging

XVI.ab Imaging: Cavitating/cavitary lung nodule, mass or nodules (see also Iq, XIs, XIIi, XVIaa and XVIIp)

XVII. Infections & related conditions

XVII.p Lung abscess/abscesses (see also VIr)

I. Interstitial/parenchymal lung disease

I.n Pulmonary alveolar proteinosis (PAP)

II. Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

III. Pulmonary/alveolar./airway hemorrhage/bleeding

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

IV. Airway involvement

IV.e Cough (acute, violent, explosive)

IV. Airway involvement

IV.g Cough syncope

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.c Upper airway obstruction other than angioedema or hematoma

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.e Laryngospasm (a.k.a. laryngismus)

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.h Vocal cord dysfunction, adduction, closure, injury

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.q Tongue involvement (edema, glossitis, hematoma)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.c Chest wall muscle rigidity - Stiff/wooden chest

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.i Respiratory arrest - Apnea

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.t CNS involvement/dysfunction/damage

X. Systemic/Distant conditions, syndromes and reactions

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

XI. Miscellaneous

XI.g Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

XI. Miscellaneous

XI.r Death following exposure or poisoning

XII. Cardiovascular involvement / toxicity

XII.f Cardiomyopathy (acute, subacute, chronic)

XII. Cardiovascular involvement / toxicity

XII.n Cardiovascular collapse - Cardiogenic shock - Hypotension

II. Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

II. Pulmonary edema - Acute lung injury - ARDS

II.b ARDS - Acute lung injury

II. Pulmonary edema - Acute lung injury - ARDS

II.f Hypoxemia, low oxygen saturation (may occur in isolation)

II. Pulmonary edema - Acute lung injury - ARDS

II.i Flash (fulminate) pulmonary edema

IV. Airway involvement

IV.a Bronchospasm - Wheezing - Asthma

IV. Airway involvement

IV.b Bronchospasm and angioedema

IV. Airway involvement

IV.d Cough (lone)

IV. Airway involvement

IV.e Cough (acute, violent, explosive)

IV. Airway involvement

IV.f Severe or catastrophic bronchospasm or asthma attack (can be fatal)

VI. Pulmonary vasculopathy

VI.e Fat/oil embolism - The FES embolism syndrome

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.h Vocal cord dysfunction, adduction, closure, injury

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.i Respiratory arrest - Apnea

IX. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

IX.p Disordered breathing during sleep - Sleep apnea

X. Systemic/Distant conditions, syndromes and reactions

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

X. Systemic/Distant conditions, syndromes and reactions

X.u Multiple organ dysfunction/failure (MODS/MOF)

X. Systemic/Distant conditions, syndromes and reactions

X.aa Propofol infusion syndrome (PRIS)

XI. Miscellaneous

XI.d Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea

XI. Miscellaneous

XI.r Death following exposure or poisoning

XI. Miscellaneous

XI.x Addictive risk

XII. Cardiovascular involvement / toxicity

XII.a Left or biventricular dysfunction/failure

XII. Cardiovascular involvement / toxicity

XII.m Cardiac- cardiorespiratory/pulmonary arrest

XII. Cardiovascular involvement / toxicity

XII.n Cardiovascular collapse - Cardiogenic shock - Hypotension

XII. Cardiovascular involvement / toxicity

XII.w Asystole

XV. Pathology

XV.ae Path: Lipid/fat embolism (see also VIe)

XXIV. Veterinary medicine

XXIV.h Veterinary: Anaphylaxis/Anaphylactoid reaction

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.y Progression, acceleration or exacerbation of preexisting ILD/fibrosis

VIII. Central-large-upper airway (incl. pharyngeal-nasal) involvement

VIII.h Vocal cord dysfunction, adduction, closure, injury

X. Systemic/Distant conditions, syndromes and reactions

X.k Sarcoid-like granulomatosis (endo-/extrathoracic)

XII. Cardiovascular involvement / toxicity

XII.c Pericardial effusion (w/wo tamponade)

XVII. Infections & related conditions

XVII.b Opportunistic pulmonary/systemic infections

XVII. Infections & related conditions

XVII.g Tuberculosis (pulmonary, pulmonary, extrapulmonary or disseminated). Reactivation or de novo

XVII. Infections & related conditions

XVII.ah Pulmonary pasteurellosis