The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVIII.b

Respiratory dyskinesia

May predispose to gasping and aspiration pneumonia

Publications

Bhimanil MM, Khan MM, Khan MF, Waris MS

Respiratory dyskinesia--an under-recognized side-effect of neuroleptic medications.

JPMA. The Journal of the Pakistan Medical Association 2011 Sep;61;930-2 — 2011 Sep — 930-2

Fève A, Angelard B, Fénelon G, Logak M, Guillard A, Lacau Saint-Guily J

Postneuroleptic laryngeal dyskinesias: a cause of upper airway obstructive syndrome improved by local injections of botulinum toxin.

Movement disorders : official journal of the Movement Disorder Society 1993 Apr;8;217-9 — 1993 Apr — 217-9

Brown LK

What respiratory abnormalities result from neuroleptics and levodopa?

Chest 1995 Aug;108;591-2 — 1995 Aug — 591-2

Kruk J, Sachdev P, Singh S

Neuroleptic-induced respiratory dyskinesia.

The Journal of neuropsychiatry and clinical neurosciences 1995;7;223-9 — 1995 — 223-9