The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Propofol anaphylaxis may be related to soybean in the vehicle (PMID 22211170)

Publications

Lee SJ, Kim SI, Jung BI, Lee SM, Kim MG, Park SY, Kim SH, Ok SY

Suspected anaphylactic reaction associated with microemulsion propofol during anesthesia induction.

Journal of Korean medical science 2012 Jul;27;827-9 — 2012 Jul — 827-9

Tsai MH, Kuo PH, Hong RL, Yang PC

Anaphylaxis after propofol infusion for Port-A-Cath insertion in a 35-year old man.

Journal of the Formosan Medical Association = Taiwan yi zhi 2001 Jun;100;424-6 — 2001 Jun — 424-6