The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XI.o

Death following exposure or poisoning

Publications

Han E, Jung S, Baeck S, Lee S, Chung H

Deaths from recreational use of propofol in Korea.

Forensic science international 2013 Dec 10;233;333-7 — 2013 Dec 10 — 333-7

Lyons B

Medical manslaughter.

Irish medical journal 2013 Jan;106;26-7 — 2013 Jan — 26-7

Roussin A, Mirepoix M, Lassabe G, Dumestre-Toulet V, Gardette V, Montastruc JL, Lapeyre-Mestre M

Death related to a recreational abuse of propofol at therapeutic dose range.

British journal of anaesthesia 2006 Aug;97;268 — 2006 Aug — 268