The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Propofol infusion syndrome (PRIS)

Publications

Mayette M, Gonda J, Hsu JL, Mihm FG

Propofol infusion syndrome resuscitation with extracorporeal life support: a case report and review of the literature.

Annals of intensive care. 2013;3(1):32

Fudickar A, Bein B

Propofol infusion syndrome: update of clinical manifestation and pathophysiology.

Minerva anestesiologica. 2009;75(5):339-44

Romero P C, Morales R M, Donaire R L, Llanos V O, Cornejo R R, Gálvez A R, Castro O J

[Severe lactic acidosis caused by propofol infusion: report of one case].

Revista medica de Chile. 2008;136(1):88-92

Fodale V, La Monaca E

Propofol infusion syndrome: an overview of a perplexing disease.

Drug safety. 2008;31(4):293-303

Kam PC, Cardone D

Propofol infusion syndrome.

Anaesthesia. 2007;62(7):690-701

Fudickar A, Bein B, Tonner PH

Propofol infusion syndrome in anaesthesia and intensive care medicine.

Current opinion in anaesthesiology. 2006;19(4):404-10