The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.b

ARDS - Acute lung injury

Publications

Saboo K, Gemnani RR, Sharma S, Kumar S, Acharya S

Chemical Pneumonitis and Reactive Airways Dysfunction Syndrome After Fumigation Exposure to Dimethanol and Glutaraldehyde: A Silent Menace Unmasked.

Cureus. 2023;15(8):e42939

Morita S, Takimoto T, Kawahara K, Nishi K, lino M

Clinical course of acute chemical lung injury caused by 3-chloropentafluoropene.

BMJ case reports. 2013;2013

Wiel E, Sicot J, Leteurtre S, Binoche A, Nisse P, Assez N

[Sodium dichloroisocyanurate-induced acute lung injury in a child].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie. 2013;20(4):375-7

Karr C

Children's environmental health in agricultural settings.

Journal of agromedicine. 2012;17(2):127-39

Blow BJ, Ge Y, Safdar Z

Respiratory failure, lung infiltrates, and hemoptysis in a woman with chronic isopropyl alcohol inhalation.

Therapeutic advances in respiratory disease. 2012;6(3):189-93

Spangenberg T, Grahn H, van der Schalk H, Kuck KH

[Paraquat poisoning. Case report and overview].

Medizinische Klinik, Intensivmedizin und Notfallmedizin. 2012;107(4):270-4

Ra SW, Byun S, Kwon WJ, Hong ES, Kim Y

Chemical pneumonitis after intravenous injection of isoparaffin: Characteristic clinico-radiologic findings.

Clinical toxicology (Philadelphia, Pa.). 2011;49(10):942-3

Centers for Disease Control and Prevention (CDC)

Sexual transmission of hepatitis C virus among HIV-infected men who have sex with men--New York City, 2005-2010.

MMWR. Morbidity and mortality weekly report. 2011;60(28):945-50

Mohan A, Kumar SN, Rao MH, Bollineni S, Manohar IC

Acute accidental exposure to chlorine gas: clinical presentation, pulmonary functions and outcomes.

The Indian journal of chest diseases & allied sciences. 2010;52(3):149-52

Lee J, Lee C, Kim CH

Uncontrolled occupational exposure to 1,1-dichloro-1-Fluoroethane (HCFC-141b) is associated with acute pulmonary toxicity.

Chest. 2009;135(1):149-155

Vernez D, Bruzzi R, Kupferschmidt H, De-Batz A, Droz P, Lazor R

Acute respiratory syndrome after inhalation of waterproofing sprays: a posteriori exposure-response assessment in 102 cases.

Journal of occupational and environmental hygiene. 2006;3(5):250-61

Goldstein DA, Johnson G, Farmer DR, Martens MA, Ford JE, Cullen MR

Pneumonitis and herbicide exposure.

Chest. 1999;116(4):1139-40

Pushnoy LA, Avnon LS, Carel RS

Herbicide (Roundup) pneumonitis.

Chest. 1998;114(6):1769-71

White CS, Templeton PA

Chemical pneumonitis.

Radiologic clinics of North America. 1992;30(6):1231-43