The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLII.a

Alveolar hemorrhage (AH), diffuse AH (DAH)

Publications

de Prost N, Parrot A, Cuquemelle E, Picard C, Antoine M, Fleury-Feith J, Mayaud C, Boffa JJ, Fartoukh M, Cadranel J

Diffuse alveolar hemorrhage in immunocompetent patients: etiologies and prognosis revisited.

Respiratory medicine 2012 Jul;106;1021-32 — 2012 Jul — 1021-32

Schloneger M, Stull A, Singer JI

Inhalant abuse: a case of hemoptysis associated with halogenated hydrocarbons abuse.

Pediatric emergency care 2009 Nov;25;754-7 — 2009 Nov — 754-7

Lazor R, Bigay-Gamé L, Cottin V, Cadranel J, Decaux O, Fellrath JM, Cordier JF, ,

Alveolar hemorrhage in anti-basement membrane antibody disease: a series of 28 cases.

Medicine 2007 May;86;181-93 — 2007 May — 181-93

Za?eska M, Zych J, Oniszh K, Rowi?ska-Zakrzewska E

[Alveolar hemorrhage caused by exposure to pesticides].

Pneumonologia i alergologia polska 2001;69;206-10 — 2001 — 206-10

Kaplan V, Baur X, Czuppon A, Ruegger M, Russi E, Speich R

Pulmonary hemorrhage due to inhalation of vapor containing pyromellitic dianhydride.

Chest 1993 Aug;104;644-5 — 1993 Aug — 644-5