The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VI.e

Fat/oil embolism - The FES embolism syndrome

Publications

Chondrogiannis KD, Siontis GC, Koulouras VP, Lekka ME, Nakos G

Acute lung injury probably associated with infusion of propofol emulsion.

Anaesthesia 2007 Aug;62;835-7 — 2007 Aug — 835-7

Guo SL

Respiratory failure after pneumonectomy in a patient with unknown hyperlipidemia.

Anesthesia and analgesia 2002 Jun;94;1672; author reply 1672-3 — 2002 Jun — 1672; author reply 1672-3

el-Ebiary M, Torres A, Ramirez J, Xaubet A, Rodriguez-Roisin R

Lipid deposition during the long-term infusion of propofol.

Critical care medicine 1995 Nov;23;1928-30 — 1995 Nov — 1928-30