The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pleural/pericardial effusion, ANA positive (DI lupus)
Publications
Dangers in the use of some potent drugs.
Canadian Medical Association journal 1962 Dec 15;87;1275-81 — 1962 Dec 15 — 1275-81
Rheumatic and febrile syndrome during prolonged hydralazine treatment.
Journal of the American Medical Association 1954 Jan 02;154;23-9 — 1954 Jan 02 — 23-9