The Drug-Induced Respiratory Disease Website and App

XLVIII.c

XLVIII - Neuromuscular / CNS involvement - Disordered breathing (during sleep)

Chest wall muscle rigidity - Stiff/wooden chest

Last update 31/07/2022

Stiff chest from chest wall/respiratory muscle spasm or contracture. May cause apnea, acute respiratory compromise/failure and death. May associate with tetany and/or laryngospasm (see also VIIIe and IXi)

Causative drugs

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases