The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVIII.c

Chest wall muscle rigidity - Stiff/wooden chest

See also Case Records of the Massachusetts General Hospital - Case 12-2001. N Engl J Med 2001; 344 (16): 1232-9 (PMID 11309639)

Publications

Shadnia S, Moiensadat M, Abdollahi M

A case of acute strychnine poisoning.

Veterinary and human toxicology 2004 Apr;46;76-9 — 2004 Apr — 76-9

Palatnick W, Meatherall R, Sitar D, Tenenbein M

Toxicokinetics of acute strychnine poisoning.

Journal of toxicology. Clinical toxicology 1997;35;617-20 — 1997 — 617-20

Boyd RE, Brennan PT, Deng JF, Rochester DF, Spyker DA

Strychnine poisoning. Recovery from profound lactic acidosis, hyperthermia, and rhabdomyolysis.

The American journal of medicine 1983 Mar;74;507-12 — 1983 Mar — 507-12

Perper JA

Fatal strychnine poisoning--a case report and review of the literature.

Journal of forensic sciences 1985 Oct;30;1248-55 — 1985 Oct — 1248-55