The Drug-Induced Respiratory Disease Website and App

Dinitrophenol (2, 4-dinitrophenol or DNP)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.u

Multiple organ dysfunction/failure (MODS/MOF)

Publications

Agrawal A, Gutch M, Arora R, Jain N

Acute cardiogenic pulmonary oedema with multiorgan dysfunction--still to learn more about nitrobenzene poisoning.

BMJ case reports. 2011;2011

Bartlett J, Brunner M, Gough K

Deliberate poisoning with dinitrophenol (DNP): an unlicensed weight loss pill.

Emergency medicine journal : EMJ. 2010;27(2):159-60