The Drug-Induced Respiratory Disease Website and App

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.al Pleuropneumonitis

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.b Eosinophilic pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.c Pleural thickening - Fibrothorax

XLV. Pleural and/or pericardial involvement

XLV.m Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

XLVII. Mediastinal involvement

XLVII.d Fibrosing mediastinitis

LI. Cardiovascular involvement / toxicity

LI.b Valvular heart disease and/or dysfunction

LI. Cardiovascular involvement / toxicity

LI.g Cardiomyopathy (acute, subacute, chronic)

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.z Progression, acceleration or exacerbation of preexisting ILD/fibrosis

I. Interstitial/parenchymal lung disease

I.ap Pulmonary infiltrates

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.h Major/massive hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.l Alveolar hemorrhage, localized (e.g. lobar)

XLIII. Airway involvement

XLIII.n Bronchial wall erosion/hematoma

XLIII. Airway involvement

XLIII.ab Cough (lone)

XLIII. Airway involvement

XLIII.ak Bronchopericardial fistula

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.d Laryngeal disorder-Laryngeal nerve palsy (dysphonia, hoarseness)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.f Vocal cord dysfunction, adduction, closure, injury

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.e Hemothorax - Serosanguineous pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.n Hemopericardium - Bloody pericardial effusion

XLVI. Pulmonary vasculopathy

XLVI.b Pulmonary arterial hypertension

XLVI. Pulmonary vasculopathy

XLVI.o Air/gas embolism

XLVI. Pulmonary vasculopathy

XLVI.y Pulmonary vein stenosis

XLVI. Pulmonary vasculopathy

XLVI.ab Pulmonary infarction

XLVI. Pulmonary vasculopathy

XLVI.ad Pulmonary vein perforation/rupture

XLVII. Mediastinal involvement

XLVII.d Fibrosing mediastinitis

XLVII. Mediastinal involvement

XLVII.g Hemomediastinum - Mediastinal hematoma

XLVII. Mediastinal involvement

XLVII.h Pneumomediastinum

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.j Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.n Vagal nerve injury (may cause GE reflux/GERD)

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.i Esophageal hematoma (may cause chest pain and/or tracheal compression)

LI. Cardiovascular involvement / toxicity

LI.c Pericardial effusion (w/wo tamponade)

LI. Cardiovascular involvement / toxicity

LI.h Coronary artery disease (acute) - Myocardial ischemia/infarction

LI. Cardiovascular involvement / toxicity

LI.aa Pneumopericardium

LI. Cardiovascular involvement / toxicity

LI.ah Coronary vasospasm - Vasospastic angina

LI. Cardiovascular involvement / toxicity

LI.ay Postcardiac/-cardiotomy injury (PCIS-Dressler syndrome)

LI. Cardiovascular involvement / toxicity

LI.bg Perforation of the heart - Cardiac rupture

LI. Cardiovascular involvement / toxicity

LI.bj Atrio-esophageal fistula

LI. Cardiovascular involvement / toxicity

LI.bk Atrial septal defect, acquired

LI. Cardiovascular involvement / toxicity

LI.bn Pulmonary vein thrombosis

LI. Cardiovascular involvement / toxicity

LI.bz Pericardial-esophageal fistula

LII. Esophageal involvement

LII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

LV. Imaging

LV.b Imaging: Ground-glass opacities (GGO) / shadowing

LV. Imaging

LV.l Imaging: Peribronchovascular areas of consolidation

LV. Imaging

LV.bi Imaging: Pulmonary vein stenosis

LV. Imaging

LV.br Imaging: Localized calcification of pulmonary vein or veins

LVIII. Pathology

LVIII.r Path: Alveolar hemorrhage (see also IIIa)

LVIII. Pathology

LVIII.s Path: Pulmonary congestion

LVIII. Pathology

LVIII.bd Path: Pulmonary veno-occlusive disease (PVOD)

LVIII. Pathology

LVIII.da Path: Pulmonary vein stenosis

LIX. Infections & related conditions

LIX.a Respiratory tract infection incl. pneumonia

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.al Pleuropneumonitis

XLIII. Airway involvement

XLIII.a Bronchospasm - Wheezing - Asthma

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.c Pleural thickening - Fibrothorax

XLV. Pleural and/or pericardial involvement

XLV.h Chylothorax

XLV. Pleural and/or pericardial involvement

XLV.m Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

XLV. Pleural and/or pericardial involvement

XLV.o The 'folded lung' (Blesovsky syndrome)

XLVII. Mediastinal involvement

XLVII.d Fibrosing mediastinitis

L. Miscellaneous

L.r Chest pressure/discomfort

L. Miscellaneous

L.an Retroperitoneal fibrosis

LI. Cardiovascular involvement / toxicity

LI.a Left or biventricular dysfunction/failure

LI. Cardiovascular involvement / toxicity

LI.b Valvular heart disease and/or dysfunction

LI. Cardiovascular involvement / toxicity

LI.c Pericardial effusion (w/wo tamponade)

LI. Cardiovascular involvement / toxicity

LI.h Coronary artery disease (acute) - Myocardial ischemia/infarction

LV. Imaging

LV.ap Imaging: Pleural effusion

LV. Imaging

LV.ar Imaging: Pleural thickening w/wo rounded atelectasis

LVIII. Pathology

LVIII.bm Path: Pleuritis, pleural fibrosis

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.i Subclinical pulmonary infiltrates/ILD

I. Interstitial/parenchymal lung disease

I.p Focal/localized area of pneumonitis/fibrosis

I. Interstitial/parenchymal lung disease

I.w Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

I. Interstitial/parenchymal lung disease

I.y Pleuroparenchymal fibroelastosis (PPFE)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLIII. Airway involvement

XLIII.j Bronchiectasis

XLIII. Airway involvement

XLIII.ai Bronchial stenosis/stricture

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.c Upper airway obstruction other than angioedema or hematoma

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.d Laryngeal disorder-Laryngeal nerve palsy (dysphonia, hoarseness)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.g Vocal cord paresis/paralysis

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.s Tracheal/large airway necrosis, chondronecrosis, perforation

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.aa Pseudomembranous tracheitis/tracheobronchitis

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ab Airway (e.g. tracheoesophageal) fistula

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ac Large airway necrosis

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.b Eosinophilic pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.c Pleural thickening - Fibrothorax

XLV. Pleural and/or pericardial involvement

XLV.f Pneumothorax

XLV. Pleural and/or pericardial involvement

XLV.h Chylothorax

XLV. Pleural and/or pericardial involvement

XLV.l Malignant pleural mesothelioma

XLV. Pleural and/or pericardial involvement

XLV.m Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

XLV. Pleural and/or pericardial involvement

XLV.u The apical cap

XLVI. Pulmonary vasculopathy

XLVI.c Pulmonary veno-occlusive disease

XLVI. Pulmonary vasculopathy

XLVI.r Pulmonary artery aneurysm(s)

XLVI. Pulmonary vasculopathy

XLVI.aa Pulmonary artery stenosis

XLVII. Mediastinal involvement

XLVII.d Fibrosing mediastinitis

XLVII. Mediastinal involvement

XLVII.i Mediastinitis

XLVII. Mediastinal involvement

XLVII.j Compression of mediastinal structures/organs

XLVII. Mediastinal involvement

XLVII.l Calcification of mediastinal lymph nodes

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.a Diaphragm/inspiratory muscle weakness/paralysis (w/wo ARF)

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.aj Paraspinal muscle myositis/myopathy/neuromyopathy +- the dropped head syndrome

L. Miscellaneous

L.h Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

L. Miscellaneous

L.m Chest deformity: platythorax

L. Miscellaneous

L.s Rib fracture

L. Miscellaneous

L.ad Vertebral compression fracture

L. Miscellaneous

L.bc Aorto-esophageal fistula

L. Miscellaneous

L.bn Dropped-head syndrome

LI. Cardiovascular involvement / toxicity

LI.a Left or biventricular dysfunction/failure

LI. Cardiovascular involvement / toxicity

LI.b Valvular heart disease and/or dysfunction

LI. Cardiovascular involvement / toxicity

LI.g Cardiomyopathy (acute, subacute, chronic)

LI. Cardiovascular involvement / toxicity

LI.h Coronary artery disease (acute) - Myocardial ischemia/infarction

LI. Cardiovascular involvement / toxicity

LI.l Constrictive pericarditis - Pericardial thickening

LI. Cardiovascular involvement / toxicity

LI.p Coronary artery disease (subacute, chronic)

LI. Cardiovascular involvement / toxicity

LI.t Heart block (bundle branch- or AV-)

LI. Cardiovascular involvement / toxicity

LI.af Effusive-constrictive pericarditis

LI. Cardiovascular involvement / toxicity

LI.am Late left ventricular dysfunction/failure

LI. Cardiovascular involvement / toxicity

LI.ap Pericardial calcification

LI. Cardiovascular involvement / toxicity

LI.bf Coarctation of the aorta (acquired)

LI. Cardiovascular involvement / toxicity

LI.bx Aortoesophageal fistula

LII. Esophageal involvement

LII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

LII. Esophageal involvement

LII.c Esophageal stenosis/stricture

LII. Esophageal involvement

LII.d Esophageal toxicity

LV. Imaging

LV.ac Imaging: Cavitating/cavitary lung nodule, mass or nodules (see also Iq, XIs, XIIi, XVIaa and XVIIp)

LV. Imaging

LV.bm Imaging: Hyperlucent lung

LV. Imaging

LV.bn Imaging: Atelectasis (a combination of increased density and volume loss. Typically lobar)

LV. Imaging

LV.bp Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

LVIII. Pathology

LVIII.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

LVIII. Pathology

LVIII.x Path: Pulmonary fibrosis (not otherwise specified or unclassifiable)

LX. Neoplastic conditions

LX.a Lung cancer

LX. Neoplastic conditions

LX.d Malignant mesothelioma (pleural, pericardial)

LX. Neoplastic conditions

LX.e Breast cancer

LX. Neoplastic conditions

LX.j Pulmonary synovial sarcoma

LX. Neoplastic conditions

LX.l Chondrosarcoma

LX. Neoplastic conditions

LX.m Tumor of the heart

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.i Subclinical pulmonary infiltrates/ILD

I. Interstitial/parenchymal lung disease

I.l Lung nodule or nodules

I. Interstitial/parenchymal lung disease

I.m Diffuse alveolar damage (DAD) (see alsoo under IIb and XVf)

I. Interstitial/parenchymal lung disease

I.p Focal/localized area of pneumonitis/fibrosis

I. Interstitial/parenchymal lung disease

I.w Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

I. Interstitial/parenchymal lung disease

I.y Pleuroparenchymal fibroelastosis (PPFE)

I. Interstitial/parenchymal lung disease

I.z Progression, acceleration or exacerbation of preexisting ILD/fibrosis

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.h Major/massive hemoptysis

XLIII. Airway involvement

XLIII.ai Bronchial stenosis/stricture

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.c Upper airway obstruction other than angioedema or hematoma

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.g Vocal cord paresis/paralysis

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.s Tracheal/large airway necrosis, chondronecrosis, perforation

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ab Airway (e.g. tracheoesophageal) fistula

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ac Large airway necrosis

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.c Pleural thickening - Fibrothorax

XLV. Pleural and/or pericardial involvement

XLV.f Pneumothorax

XLV. Pleural and/or pericardial involvement

XLV.h Chylothorax

XLV. Pleural and/or pericardial involvement

XLV.k Pleural calcifications

XLVI. Pulmonary vasculopathy

XLVI.c Pulmonary veno-occlusive disease

XLVI. Pulmonary vasculopathy

XLVI.w Pulmonary lymphangiectasis

XLVII. Mediastinal involvement

XLVII.d Fibrosing mediastinitis

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.j Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.t Cavitation/necrosis of lung tumor or metastases

L. Miscellaneous

L.ad Vertebral compression fracture

LI. Cardiovascular involvement / toxicity

LI.b Valvular heart disease and/or dysfunction

LI. Cardiovascular involvement / toxicity

LI.l Constrictive pericarditis - Pericardial thickening

LI. Cardiovascular involvement / toxicity

LI.p Coronary artery disease (subacute, chronic)

LI. Cardiovascular involvement / toxicity

LI.t Heart block (bundle branch- or AV-)

LII. Esophageal involvement

LII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

LII. Esophageal involvement

LII.d Esophageal toxicity

LII. Esophageal involvement

LII.e Esophageal dysmotility

LV. Imaging

LV.bp Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.a BAL: An excess proportion of lymphocytes

LVIII. Pathology

LVIII.d Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

LVIII. Pathology

LVIII.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

LVIII. Pathology

LVIII.q Path: Pneumocyte atypia (reactive epithelial cells) (a.k.a. the "Napoleon Hat" sign)

LVIII. Pathology

LVIII.v Path: NSIP-fibrotic pattern

LVIII. Pathology

LVIII.cg Path: Diffuse lymphangiectasis

LIX. Infections & related conditions

LIX.e Pneumocystis jiroveci pneumonia

LIX. Infections & related conditions

LIX.ae Reactivation of a prior pulmonary infection (TB, melioidosis)

LX. Neoplastic conditions

LX.e Breast cancer