The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Prieto García A, Pineda de la Losa F

Immunoglobulin E-mediated severe anaphylaxis to paclitaxel.

Journal of investigational allergology & clinical immunology 2010;20;170-1 — 2010 — 170-1

Kloover JS, den Bakker MA, Gelderblom H, van Meerbeeck JP

Fatal outcome of a hypersensitivity reaction to paclitaxel: a critical review of premedication regimens.

British journal of cancer 2004 Jan 26;90;304-5 — 2004 Jan 26 — 304-5