The Drug-Induced Respiratory Disease Website and App

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.h Dyspnea, unexplained otherwise

LIX. Infections & related conditions

LIX.b Opportunistic pulmonary/systemic infections

LIX. Infections & related conditions

LIX.e Pneumocystis jiroveci pneumonia

LIX. Infections & related conditions

LIX.af CMV pneumonitis (reactivation)

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.d Acute eosinophilic pneumonia (AEP)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.f Acute fibrinous organizing pneumonia (AFOP)

I. Interstitial/parenchymal lung disease

I.k Exogenous lipoid pneumonia (subacute, acute)

I. Interstitial/parenchymal lung disease

I.n ILD with a granulomatous component

I. Interstitial/parenchymal lung disease

I.o Pulmonary alveolar proteinosis (PAP)

I. Interstitial/parenchymal lung disease

I.v Relapsing or migrating pneumonitis/pneumonia (see also Id)

I. Interstitial/parenchymal lung disease

I.w Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

I. Interstitial/parenchymal lung disease

I.ax Persistent reduction in diffusing capacity for CO upon resolution of the adverse effect

I. Interstitial/parenchymal lung disease

I.ay Chronic pneumonitis

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.u Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.m Coagulopathy

XLIII. Airway involvement

XLIII.a Bronchospasm - Wheezing - Asthma

XLIII. Airway involvement

XLIII.b Severe or catastrophic bronchospasm or asthma attack (can be fatal)

XLIII. Airway involvement

XLIII.e Deterioration/exacerbation of preexisting asthma or COPD

XLIII. Airway involvement

XLIII.h Reactive airway dysfunction syndrome (RADS)

XLIII. Airway involvement

XLIII.j Bronchiectasis

XLIII. Airway involvement

XLIII.l Large airway inflammation - Tracheitis (w/wo tissue eosinophilia)

XLIII. Airway involvement

XLIII.p Thermal, chemical or caustic airway injury

XLIII. Airway involvement

XLIII.u Sptutum production - Bronchorrhea - 'Bronchitis'

XLIII. Airway involvement

XLIII.ab Cough (lone)

XLIII. Airway involvement

XLIII.af Sputum production - Bonchorrhea - ‘Bronchitis’

XLIII. Airway involvement

XLIII.ag Obstructive airway dysfunction (see also IVc, XVx)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.i Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.p Foreign body in the airway

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.am Epiglottitis

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ao Facial/labial/buccal/oral/dental trauma

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.aq Airway foreign body

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.av Gross tracheal inflammation on endoscopy

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.ax Tracheitis including eosinophilic tracheal inflammation

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.az Tracheal redness/inflammation on gross endoscopic examination

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.f Pneumothorax

XLVII. Mediastinal involvement

XLVII.a Lymphadenopathy (intrathoracic)

XLVII. Mediastinal involvement

XLVII.e Granulomatous mediastinal lymphadenopathy

XLVII. Mediastinal involvement

XLVII.h Pneumomediastinum

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.h Dyspnea, unexplained otherwise

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.af Seizures

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.b Antiphospholipid antibodies w/wo the APL syndrome

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.m Sarcoid-like granulomatosis (endo-/extrathoracic)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.s Systemic inflammatory response

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.as Relapse or flare of preexisting ulcerative colitis

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.o Death following exposure or poisoning

L. Miscellaneous

L.z Thermal skin/dermal injury

L. Miscellaneous

L.at Chest tightness

L. Miscellaneous

L.aw Polycythemia

L. Miscellaneous

L.ax Nicotine poisoning

L. Miscellaneous

L.ay Burns

LI. Cardiovascular involvement / toxicity

LI.a Left or biventricular dysfunction/failure

LI. Cardiovascular involvement / toxicity

LI.n Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

LI. Cardiovascular involvement / toxicity

LI.ai Bradycardia

LIII. Hemoglobinopathies - Abnormal hemoglobin states (acquired)

LIII.a Methemoglobinemia

LV. Imaging

LV.a Imaging: Diffuse haze

LV. Imaging

LV.b Imaging: Ground-glass opacities (GGO) / shadowing

LV. Imaging

LV.d Imaging: Alveolar opacities or haze with a batwing or butterfly distribution

LV. Imaging

LV.g Imaging: Diffuse whiteout/alveolar shadowing (see also under IIb-ARDS)

LV. Imaging

LV.k Imaging: An area or areas of consolidation

LV. Imaging

LV.v Imaging: Centrilobular micronodules (can be diffuse)

LV. Imaging

LV.ad Imaging: Lung cysts or bullae (see also XVI ah/bf)

LV. Imaging

LV.ak Imaging: A 'tree-in-bud' pattern

LV. Imaging

LV.bp Imaging: An area or areas of avid tracer uptake in the lung/chest on 18F-PET scan

LVI. Distinctive patterns - 'Eye-catchers'

LVI.x Eye catcher: A batwing pattern on imaging

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.a BAL: An excess proportion of lymphocytes

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.b BAL: An excess proportion of neutrophils

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.c BAL: An excess proportion of eosinophils

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.d BAL: Gross or microscopic bleeding/hemorrhage

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.f BAL: Foamy macrophages

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.i BAL: Oil red O-stainable material in BAL macrophages othen than exogenous lipids

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.n BAL: Brown-pigmented macrophages

LVIII. Pathology

LVIII.d Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

LVIII. Pathology

LVIII.e Path: Acute fibrinous organizing pneumonia (AFOP-pattern) (see also If)

LVIII. Pathology

LVIII.f Path: ILD with a granulomatous component (see also Im)

LVIII. Pathology

LVIII.l Path: Giant-cell interstitial pneumonia (GIP)-pattern

LVIII. Pathology

LVIII.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

LVIII. Pathology

LVIII.r Path: Alveolar hemorrhage (see also IIIa)

LVIII. Pathology

LVIII.z Path: Exogenous lipoid pneumonia

LVIII. Pathology

LVIII.al Path: Acute/subacute bronchiolitis (see also IVc, IVi)

LVIII. Pathology

LVIII.ap Path: Respiratory bronchiolitis (w/wo the RB-ILD-pattern)

LVIII. Pathology

LVIII.bc Path: Pulmonary capillaritis

LVIII. Pathology

LVIII.bx Path: Granulomatous lymphadenopathy

LIX. Infections & related conditions

LIX.a Respiratory tract infection incl. pneumonia

LIX. Infections & related conditions

LIX.c Aspergillosis, pulmonary (invasive, allergic [ABPA], or mycetoma)

LIX. Infections & related conditions

LIX.h Nontuberculous pulmonary mycobacterial infection/superinfection

LIX. Infections & related conditions

LIX.ab Actinomycosis