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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.d

Cough (lone)

Publications

Benyo SE, Bruinsma TJ, Drda E, Brady-Olympia J, Hicks SD, Boehmer S, Olympia RP

Risk Factors and Medical Symptoms Associated With Electronic Vapor Product Use Among Adolescents and Young Adults.

Clinical pediatrics. 2021;60(6-7):279-289

King JL, Reboussin BA, Merten JW, Wiseman KD, Wagoner KG, Sutfin EL

Negative health symptoms reported by youth e-cigarette users: Results from a national survey of US youth.

Addictive behaviors. 2020;104:106315

Giovanni SP, Keller TL, Bryant AD, Weiss NS, Littman AJ

Electronic Cigarette Use and Chronic Respiratory Symptoms among U.S. Adults.

American journal of respiratory and critical care medicine. 2020;201(9):1157-1160

Hua M, Sadah S, Hristidis V, Talbot P

Health Effects Associated With Electronic Cigarette Use: Automated Mining of Online Forums.

Journal of medical Internet research. 2020;22(1):e15684

King JL, Reboussin BA, Wiseman KD, Ribisl KM, Seidenberg AB, Wagoner KG, Wolfson M, Sutfin EL

Adverse symptoms users attribute to e-cigarettes: Results from a national survey of US adults.

Drug and alcohol dependence. 2019;196:9-13