The Drug-Induced Respiratory Disease Website and App

E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Exogenous lipoid pneumonia (subacute, acute)

See also Modi S et aL Acute lipoid pneumonia secondary to e-cigarette use: an unlikely replacement for cigarettes. Chest. 2015;148 (4): 382A. Differs from paraffin- or vaseline-induced ELP, however (PMID 31491073)

Publications

Dicpinigaitis PV, Trachuk P, Fakier F, Teka M, Suhrland MJ

Vaping-Associated Acute Respiratory Failure Due to Acute Lipoid Pneumonia.

Lung. 2020;198(1):31-33

Maddock SD, Cirulis MM, Callahan SJ, Keenan LM, Pirozzi CS, Raman SM, Aberegg SK

Pulmonary Lipid-Laden Macrophages and Vaping.

The New England journal of medicine. 2019;381(15):1488-1489

Viswam D, Trotter S, Burge PS, Walters GI

Respiratory failure caused by lipoid pneumonia from vaping e-cigarettes.

BMJ case reports. 2018;2018

Sommerfeld CG, Weiner DJ, Nowalk A, Larkin A

Hypersensitivity Pneumonitis and Acute Respiratory Distress Syndrome From E-Cigarette Use.

Pediatrics. 2018;141(6)

McCauley L, Markin C, Hosmer D

An unexpected consequence of electronic cigarette use.

Chest. 2012;141(4):1110-1113