The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Diffuse alveolar damage (DAD-pattern) (see also IL)
Publications
Fatal e-cigarette or vaping associated lung injury (EVALI): a first case report in Europe.
The European respiratory journal 2020 Mar 26;; — 2020 Mar 26
Acute Respiratory Failure Associated With Vaping.
Chest 2020 Mar;157;e63-e68 — 2020 Mar — e63-e68
Vaping-Related Lung Injury in an Adolescent.
American journal of respiratory and critical care medicine 2020 Jan 06;; — 2020 Jan 06
Mukhopadhyay S, Mehrad M, Dammert P, Arrossi AV, Sarda R, Brenner DS, Maldonado F, Choi H, Ghobrial M
Lung Biopsy Findings in Severe Pulmonary Illness Associated With E-Cigarette Use (Vaping).
American journal of clinical pathology 2020 Jan 01;153;30-39 — 2020 Jan 01 — 30-39
Butt YM, Smith ML, Tazelaar HD, Vaszar LT, Swanson KL, Cecchini MJ, Boland JM, Bois MC, Boyum JH, Froemming AT, Khoor A, Mira-Avendano I, Patel A, Larsen BT
Pathology of Vaping-Associated Lung Injury.
The New England journal of medicine 2019 Oct 02;; — 2019 Oct 02