Back to drug

The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XV.f

Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

Publications

Marlière C, De Greef J, Gohy S, Hoton D, Wallemacq P, Jacquet LM, Belkhir L

Fatal e-cigarette or vaping associated lung injury (EVALI): a first case report in Europe.

The European respiratory journal. 2020;56(1)

Fryman C, Lou B, Weber AG, Steinberg HN, Khanijo S, Iakovou A, Makaryus MR

Acute Respiratory Failure Associated With Vaping.

Chest. 2020;157(3):e63-e68

Lu MA, Jabre NA, Mogayzel PJ Jr

Vaping-related Lung Injury in an Adolescent.

American journal of respiratory and critical care medicine. 2020;201(4):481-482

Mukhopadhyay S, Mehrad M, Dammert P, Arrossi AV, Sarda R, Brenner DS, Maldonado F, Choi H, Ghobrial M

Lung Biopsy Findings in Severe Pulmonary Illness Associated With E-Cigarette Use (Vaping).

American journal of clinical pathology. 2020;153(1):30-39

Butt YM, Smith ML, Tazelaar HD, Vaszar LT, Swanson KL, Cecchini MJ, Boland JM, Bois MC, Boyum JH, Froemming AT, Khoor A, Mira-Avendano I, Patel A, Larsen BT

Pathology of Vaping-Associated Lung Injury.

The New England journal of medicine. 2019;381(18):1780-1781